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Thurl E Harris Selected Research

R 59022

1/2017Dual activities of ritanserin and R59022 as DGKα inhibitors and serotonin receptor antagonists.
7/2013Diacylglycerol kinase α is a critical signaling node and novel therapeutic target in glioblastoma and other cancers.

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Thurl E Harris Research Topics

Disease

7Neoplasms (Cancer)
01/2022 - 07/2013
7Insulin Resistance
10/2020 - 10/2008
5Obesity
01/2020 - 09/2006
3Glucose Intolerance
01/2022 - 01/2008
2Melanoma (Melanoma, Malignant)
01/2022 - 07/2013
2Rhabdomyolysis
01/2019 - 01/2015
2Glioblastoma (Glioblastoma Multiforme)
01/2018 - 07/2013
2Inflammation (Inflammations)
01/2018 - 06/2010
2Body Weight (Weight, Body)
03/2017 - 12/2012
2Tuberous Sclerosis (Bourneville's Disease)
07/2010 - 12/2003
2Fatty Liver
01/2007 - 09/2006
1COVID-19
01/2021
1Hepatomegaly
01/2021
1Infarction (Infarctions)
01/2021
1Cicatrix (Scar)
01/2021
1Ischemia
01/2021
1Respiratory Insufficiency (Respiratory Failure)
01/2021
1Myocardial Infarction
01/2021
1Burns
01/2021
1Infections
11/2020
1Intraoperative Complications
10/2020
1Hyperglycemia
10/2020
1Multiple Sclerosis
01/2020
1Hypoxia (Hypoxemia)
01/2020
1Dyslipidemias (Dyslipidemia)
01/2020
1Muscular Diseases (Myopathy)
01/2019
1Necrosis
01/2019
1Pancreatic Neoplasms (Pancreatic Cancer)
01/2018
1Prostatic Neoplasms (Prostate Cancer)
11/2017
1Carcinoma (Carcinomatosis)
11/2017
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
11/2017
1Carcinogenesis
11/2017
1Triple Negative Breast Neoplasms
01/2017
1Breast Neoplasms (Breast Cancer)
01/2017
1Schizophrenia (Dementia Praecox)
01/2017
1Substance-Related Disorders (Drug Abuse)
01/2017
1Congenital Generalized Lipodystrophy (Berardinelli-Seip Congenital Lipodystrophy)
11/2016
1Type 2 Diabetes Mellitus (MODY)
09/2015
1Starvation
04/2012
1Hypercholesterolemia
08/2011
1Lipodystrophy
09/2006

Drug/Important Bio-Agent (IBA)

10Insulin (Novolin)FDA Link
01/2022 - 01/2008
8lipineIBA
01/2019 - 09/2006
5Proteins (Proteins, Gene)FDA Link
11/2020 - 12/2003
5Phosphatidate PhosphataseIBA
01/2019 - 01/2007
4Fatty Acids (Saturated Fatty Acids)IBA
01/2021 - 01/2017
3Protein Isoforms (Isoforms)IBA
01/2022 - 08/2014
3RitanserinIBA
01/2022 - 01/2017
3Glucose (Dextrose)FDA LinkGeneric
09/2015 - 01/2008
3Triglycerides (Triacylglycerol)IBA
02/2015 - 06/2010
2AdipokinesIBA
01/2021 - 10/2020
2Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA
01/2020 - 07/2010
2DiglyceridesIBA
01/2019 - 02/2015
2Phosphatidic Acids (Phosphatidic Acid)IBA
01/2019 - 02/2015
2Diacylglycerol KinaseIBA
01/2018 - 07/2013
2R 59022IBA
01/2017 - 07/2013
2R 59949IBA
01/2017 - 07/2013
2LipidsIBA
08/2014 - 09/2006
2Mechanistic Target of Rapamycin Complex 1IBA
04/2012 - 08/2011
1AdiponectinIBA
01/2021
1Lipase (Acid Lipase)FDA Link
01/2021
1atglistatinIBA
01/2021
1ResistinIBA
10/2020
1Epinephrine (Adrenaline)FDA LinkGeneric
10/2020
1Hormones (Hormone)IBA
10/2020
1Sphingosine-1-Phosphate ReceptorsIBA
01/2020
1Oxygen (Dioxygen)IBA
01/2020
1Alpha-Ketoglutarate-Dependent Dioxygenase FTOIBA
01/2020
1geranylgeranyltransferase type-I (protein geranylgeranyltransferase)IBA
01/2018
1NF-kappa B (NF-kB)IBA
01/2018
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
11/2017
1Protein Kinase CIBA
11/2017
1Biological ProductsIBA
11/2017
1Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA
11/2017
1TensinsIBA
11/2017
1Phosphotransferases (Kinase)IBA
11/2017
1Proglucagon (Glucagon Precursors)IBA
03/2017
1CorticosteroneIBA
03/2017
1Phospholipids (Phosphatides)FDA LinkGeneric
01/2017
1Estrogen ReceptorsIBA
01/2017
1Serotonin (5 Hydroxytryptamine)IBA
01/2017
1AcyltransferasesIBA
08/2014
1CaspasesIBA
07/2013
1Small Interfering RNA (siRNA)IBA
07/2013
1GTP-Binding Proteins (G-Protein)IBA
04/2012
1CholesterolIBA
08/2011
1EnzymesIBA
03/2009
1Messenger RNA (mRNA)IBA
03/2009
1GuanosineIBA
12/2003

Therapy/Procedure

7Therapeutics
01/2022 - 07/2013
1Immunotherapy
01/2017